External resources
- Doctify website : https://www.doctify.com/uk/specialist/annamaria-minicozzi
- HCA website : https://www.hcahealthcare.co.uk/finder/stepconsultantprofile/annamaria-minicozzi
- Ms Annamaria Minicozzi Website : https://drannamariacolorectalsurgeon.com/
Current NHS consultant posts held
Consultant Colorectal, Peritoneal & Robotic
Surgeon
Barts Health NHS Trust, Royal London Hospital, UK
Honorary Reader/Associated Professor
Blizard Institute, Colorectal Cancer Genetics, Centre for Genomics and Child
Health Barts and the London School of Medicine and Dentistry
Queen Mary University of London
Research interests
Translational and Clinical Research
I have experience in translational and clinical research for colorectal cancer, in particular innovative diagnostic methods such as 3D Endorectal Ultrasound and the 1H-MRI spectroscopy to improve the staging of rectal cancer and to guide sphincter saving surgery, organ preserving surgery and Watch & Wait strategy. I also investigated the rectal cancer growth and lymph nodes metastases after inoculation of human cells HT-29 in athymic mice.
Genetics and Molecular Research
I am the principal investigator of Recare project (Watch-and-wait after chemoradiotherapy in patients with rectal cancer: biomarkers to predict response and improve safety).
I was responsible for the tissue bank of colorectal cancer at the Verona University Hospital.
Trials
I am PA of several multicentre trials and the Local investigator of numerous Barts Trials
Personal interests
Swimming
Theatre
Travel
Awards received
1. Watch-and-wait after chemoradiotherapy in patients with rectal cancer:
biomarkers to predict response and improve safety (Recare)
Barts Charity (£50,000)
2. Establishment of Cytoreductive Surgery & HIPEC/HITHOC services at RLH
and Barts to treat patients with peritoneal metastases from colorectal/
appendiceal cancer and mesothelioma
Barts Charity (£260,000).
3. Establishment of a Watch & Wait and Brachytherapy service at Barts to treat patients with rectal cancer
Barts Charity (£760,000)
(Additional) Languages spoken
Publications
A prognostic model for use before elective surgery to estimate the risk of postoperative pul-monary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts. NIHR Global Health Research Unit on Global Surgery; STARSurg Col-laborative
Humphreys DT, Lewis E, Pan-Castillo B, Berti G, Mein C, Wozniak E, Gordon H, Gadhok R, Minicozzi A, ChinAleong J, Feakins R, Giannoulatou E, James LK, Stagg AJ, Lindsay JO, Silver A. Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease. J Cell Mol Med. 2024 May;28(9):e18344. doi: 10.1111/jcmm.18344.
Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A. Epigenetic and metabolic reprogramming of fibroblasts in Crohn's disease strictures reveals histone deacetylases as therapeutic targets. J Crohns Colitis. 2023 Dec 9:jjad209. doi: 10.1093/ecco-jcc/jjad209.
ESCP EAGLE Safe Anastomosis Collaborative and NIHR Global Health Research Unit in Surgery. Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries. Br J Surg. 2024 Jan 3;111(1):znad370. doi: 10.1093/bjs/znad370.
GreenSurg Collaborative. Elective surgical services need to start planning for summer pressures.Br J Surg. 2023 Mar 30;110(4):508-510. doi: 10.1093/bjs/znad033.
8. El-Shakankery KH, Balogh P, Grantham M, Minicozzi A, Diamantis N. Ensuring No
Patient Is Lost Along the Way � A Single Centre Experience of the Clinical Genetics Referral Pathways for Lynch Syndrome. Colorectal Disease. Accettata, in attesa di pubblicazione.
10. Lewis A, S�nchez S, Berti G, Pan-Castillo B, Nijhuis A, Mehta S, Eleid L, Gordon H, Gadhok
R, Kimberley C, Minicozzi A, Chin-Aleong J, Feakins R, Kypta R, Lindsay JO, Silver A. Small-molecule Wnt inhibitors are a potential novel therapy for intestinal fibrosis in Crohns disease. Clin Sci (Lond). 2022 Oct 14;136(19):1405-1423.
Courses offered to GPs
International Society of University Colon and rectal surgeons-29th Biennal Con-gress
Corso di aggiornamento monotematico sul trattamento del cancro del colon-retto-ano
Perioperative Management in gynaeco-logical oncology
Perineal Reconstruction
Fee assured
Verified account