Current NHS consultant posts held
Consultant Neurologist
St George's University Hospital, London
Consultant Neurologist
Frimley Park Hospital, Surrey
Research interests
Novel therapeutics for Parkinson's disease, Alzheimer's disease and other neurodegenerative conditions. Novel therapeutics for genetic ataxic syndromes.
Personal interests
Rowing, rugby, spending time with my children.
Awards received
Clinical Tutor of the Year 2016, UCL Institute of Neurology
Clinical Tutor of the Year 2015, UCL Institute of Neurology
Scholarship in Medicine, Oriel College, University of Oxford
Distinction in Bachelor of Medicine examinations (Merits in Neuroscience and Pathology), University of Oxford
(Additional) Languages spoken
- French
- Conversational
- Spanish
- Conversational
Publications
Gratwicke J, Oswal A, Foltynie T. Resting state activity and connectivity of the nucleus basalis of Meynert and globus pallidus in Lewy body dementia and Parkinson’s disease dementia. Neuroimage. 2020; 221: 117184.
Gratwicke J, Zrinzo L, Akram H, McKeith I, Rossor MN, Foltynie T. Bilateral nucleus basalis of Meynert deep brain stimulation for dementia with Lewy bodies: A randomised clinical trial. Brain Stimulation. 2020; 13: 1031–1039.
Leimbach F, Gratwicke J, Foltynie T, et al. The effects of deep brain stimulation of the pedunculopontine nucleus on cognition in Parkinson’s disease and Progressive Supranuclear Palsy. Clinical Parkinsonism & Related Disorders. 2019; 1: 48–51.
Gratwicke J, Zrinzo L, Akram H, Foltynie T et al. Bilateral nucleus basalis of Meynert deep brain stimulation for Parkinson’s disease dementia: a double-blind randomised trial. JAMA Neurology. 2018 Feb 1;75(2):169-178
Gratwicke J, Foltynie T. Early nucleus basalis of Meynert degeneration predicts cognitive decline in Parkinson's disease. Brain. 2018 Jan 1;141(1):7-10.
Gratwicke J, Jahanshahi M, Foltynie T. Parkinson’s disease dementia: a neural networks perspective. Brain 2015:138; 1454-76.
Little S, Zrinzo L, Gratwicke J et al. Bilateral adaptive deep brain stimulation is effective in Parkinson's disease. J Neurol Neurosurg Psychiatry. 2016 Jul;87(7):717-21
Gratwicke J, Rees J, Edwards M. Paraneoplastic cerebellar syndrome and sensory ganglionopathy with papillary thyroid carcinoma. J Neurol Sci. 2014 Jun 15;341(1-2)
Gratwicke J, Kahan J, Foltynie T, Jahanshahi M. The nucleus basalis of Meynert: a new target for deep brain stimulation in dementia? Neurosci Biobehav Rev. 2013 Dec;37(10 Pt 2):2676-88.
Cappon D, Gratwicke J, Zrinzo L et al. Deep Brain Stimulation of the Nucleus Basalis of Meynert for Parkinson’s Disease Dementia: 36 Months Follow Up. Movement Disorders Clin. Pract. 2022;9:765–774.
Koutroumanidis M, Gratwicke J. Alpha coma EEG pattern in patients with severe COVID-19 related encephalopathy. Clinical Neurophysiology. 2021;132:218-225.
Oswal A, Neumann W-J, Gratwicke J et al. Neural signatures of hyperdirect pathway activity in Parkinson’s disease. Nature Communications. 2021;12:5185.
Oswal A, Gratwicke J, Brown P. Cortical connectivity of the nucleus basalis of Meynert in Parkinson’s disease & Lewy body dementias. Brain. 2020:1-8.
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