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Current NHS consultant posts held

Consultant Cardiologist, Oxford Heart Centre at the John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust

Research interests

My research interests include cardiac resynchronisation therapy, and site selection for the left-ventricular leads for this. Alongside this I am interested in service delivery and evaluation of heart failure services, and diuretic and medication optimisation strategy.

I am contributing to several trials currently, including of rehabilitation in heart failure, anti-inflammatory therapy for heart failure with preserved ejection fraction, and pacing strategies including left bundle branch area pacing.

Personal interests

I am kept busy by my young family. I enjoy gardening, wine, walking and travelling when time allows.

Awards received

DM Doctorate of Medicine
MRCP Membership of the Royal College of Physicians

Publications

Gamble JHP, Herring N, Ginks M, Rajappan K, Bashir Y, Betts TR: Endocardial left ventricular pacing for cardiac resynchronization: systematic review and meta-analysis. Europace 2018; 20:73-81.
Gamble JHP, Herring N, Ginks MR, Rajappan K, Bashir Y, Betts TR: Endocardial Left Ventricular Pacing across the Inter-Ventricular Septum for Cardiac Resynchronization Therapy – Clinical Results of a pilot study. Heart Rhythm 2018 – in press
Sieniewicz BJ, Behar JM, Sohal M, Gamble JHP et al. Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry. EP Europace 2018;euy052–euy052.
Sawhney V, Domenichini G, Gamble JHP, et al. Thrombo-embolic events in left ventricular endocardial pacing: long-term outcomes from a multicentre UK registry. Europace 2018; in press
Behar,… Gamble JHP et al.: Cost-Effectiveness Analysis of Quadripolar Versus Bipolar Left Ventricular Leads for Cardiac Resynchronization Defibrillator Therapy in a Large, Multicenter UK Registry. JACC: Clinical Electrophysiology 2017; 3:107–116.
Gamble JHP and Leeson PL – Reviewed and significantly revised three chapters for the Oxford Specialist Handbook of Pacing and ICDs 2018 second edition – due to be published 2018
Gamble JHP et al, Procedural success of left ventricular lead placement for cardiac resynchronization therapy – a meta-analysis. JACC: Cardiac Electrophysiology 2016; 2:69-77
Carlton, …, Gamble, et al. A Novel Diagnostic Protocol to Identify Patients Suitable for Discharge after a Single High-Sensitivity Troponin. Heart 2015;101:1041-1046
Behar,…Gamble, et al., Cardiac Resynchronization Therapy Delivered Via a Multipolar Left Ventricular Lead Is Associated with Reduced Mortality and Elimination of Phrenic Nerve Stimulation. Journal of Cardiovascular Electrophysiology 2015; 26:540
Gamble JHP, Betts TR. Multi-site left ventricular pacing in cardiac resynchronization therapy (review). Future Cardiology 2014; 10:469
Betts TR, Gamble JHP, et al. Development of a technique for left ventricular endocardial pacing via puncture of the interventricular septum. Circulation: Arrhythmia and Electrophysiology 2014; 7:17-22

Courses offered to GPs

Talks on heart failure, general cardiology, pacemakers, at the Manor Hospital Oxford or at GP practices