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Current NHS consultant posts held

Princess Alexandra Hospital NHS Trust

Publications

1. Ordonez A, Perez J, Tan L, Dickens JA, Motamedi-Shad N, Irving JA, Haq I, Ekeowa U et al. A single-chain variable fragment intrabody prevents intracellular polymerization of Z alpha1-antitrypsin while allowing its antiproteinase activity. FASEB Journal 2015; 29, 2667-2678.

2. Nyon MP, Segu L, Cabrita L, Levy G, Kirkpatrick J, Roussel B, Patschull A, Barrett T, Ekeowa U et al. Structural dynamics associated with intermediate formation in an archetypal conformational disease. Structure 2012; 20, 504-512.

3. Mungalsingh C, Bomford J, Nayagam J, Masiello M, Ekeowa UI, Webster S. Warfarin induced skin necrosis. Clinical Medicine 2012; 12, 90-91.

4. Irving J. A, Ekeowa UI et al. The serpinopathies: Studying serpin polymerisation in vivo. Methods In Enzymology 2011; 501, 241-466.

5. Chang Y. P, Mahadeva R, Patschull A, Nobeli I, Ekeowa UI, et al. Targeting Serpins in High-Throughput and Structure-Based Drug Design. Methods In Enzymology 2011; 501, 139-175.

6. Morris H, Morgan M. D, Woods A. M, Smith S. W, Ekeowa UI et al. ANCA-associated vasculitis, polymers and carriage of the Z allele of alpha1-antitrypsin. Ann Rheum Dis. 2011; 70(10), 1851-1856.

7. Roussel R. D, Irving J. A, Ekeowa UI et al. Unravelling the twists and turns of the serpinopathies. FEBS Journal 2011; 1742-4658

8. Ekeowa UI, Marciniak S. J and Lomas DA. Alpha1-antitrypsin and inflammation. Expert Review of Clinical Immunology 2011; 7(2), 243-252

9. Belorgey D, Irving J. A, Ekeowa UI et al. Characterisation of serpin polymers in vitro and in vivo. Methods 2011; 53(3), 255-266

10. Ekeowa UI, Freeke J, Miranda E et al. Defining the mechanism of polymerisation in the serpinopathies. Proceedings of the National Academy of Sciences USA 2010; 107(40), 17146-17151

11. Miranda E, Pérez J, Ekeowa UI et al. A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha1-antitrypsin deficiency. Hepatology 2010; 52(3), 1078-1088

12. Ekeowa UI and Lomas DA. Alpha1-antitrypsin deficiency. Oxford Desk Reference – Respiratory Medicine 2009

13. Ekeowa UI et al. Alpha1-antitrypsin, COPD and the Serpinopathies. Clinical Science 2009; 116, 837 – 850

14. Gooptu B, Ekeowa UI and Lomas DA. Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights. European Respiratory Journal 2009; 34, 475 – 488